San Servolo island may be reached  from the center of Venice by the public transport service actv boat line (vaporetto)  No. 20 from San Zaccaria dock (The journey takes about 10 minutes).

From Marco Polo –Venice airport

• Reach Venice city center by boat.
  Alilaguna is a boat service connecting the airport to San Marco;
  Walk from S. Marco and reach the dock of S. Zaccaria where public line No. 20 to San Servolo departs.
• Reach Venice city center by bus and boat
  ATVO is a bus service operating from 9 to 24.
  ACTV - bus n. 5 – is the public service Both connect the airport (bus departing from the arrivals terminal) with Piazzale Roma in about 25 minutes
• From Piazzale Roma to San Servolo
  Public line (vaporetto) No. 1, No. 5.1, No. 4.1, No. 6.1 or No. ° 2 direction "Lido", get off at San Zaccaria.
• From S.Zaccaria take the line (vaporetto) No. 20 for San Servolo (it may takes 10 minutes).

From Venice - S. Lucia railway station

• Public line (vaporetto) No. 1, No. 5.1, No. ° 2 direction "Lido", get off at San Zaccaria.
• From S.Zaccaria take the line (vaporetto) No. 20 for San Servolo (it may takes 10 minutes).

By car (not recommended)

If you arrive by car you can park in Piazzale Roma, Garage Comunale or Garage San Marco or Tronchetto.Park; From Piazzale Roma or Tronchetto Park take a vaporetto towards San Marco.